AVOIR rates the 2025 Mercedes-Benz E350 4matic's reliability 88/100 — excellent — from NHTSA recall counts, complaint density, and multi-year defect trends. Its overall AVOIR ownership score is 70/100 (Good).
AVOIR scores the 2025 Mercedes-Benz E350 4matic's longevity 77/100 (good), estimated from high-mileage survival data and resale-panel evidence of how far these vehicles actually run.
AVOIR scores the 2025 Mercedes-Benz E350 4matic on maintenance 67/100 and depreciation 59/100 — higher is better (lower real cost) — plus fuel, insurance and resale in the full breakdown above.
See all 2025 Mercedes-Benz E-Class trims & reliability scores.
AVOIR scores every vehicle across 7 ownership factors using EPA fuel-economy data, NHTSA safety & complaints, IIHS ratings, and a proprietary used-market resale panel.